Gene
shroom3
- ID
- ZDB-GENE-120817-1
- Name
- shroom family member 3
- Symbol
- shroom3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in glomerular visceral epithelial cell development and posterior lateral line neuromast development. Predicted to localize to several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Is expressed in intestine; otic vesicle; posterior lateral line primordium; pronephros; and spinal cord. Orthologous to human SHROOM3 (shroom family member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| chronic kidney disease | WT + MO2-shroom3 + MO4-tp53 | standard conditions | Prokop et al., 2018 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apx/Shrm Domain 1 | Apx/Shrm Domain 2 | Shroom family |
|---|---|---|---|---|
|
UniProtKB:K7X477
|
1600 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
shroom3-201
(1)
|
Ensembl | 4,695 nt | ||
| mRNA |
shroom3-202
(1)
|
Ensembl | 899 nt |
Interactions and Pathways
No data available
Plasmids
No data available