ZFIN is now using GRCz12tu for Genomic Data
Gene
pias1a
- ID
- ZDB-GENE-120727-5
- Name
- protein inhibitor of activated STAT, 1a
- Symbol
- pias1a Nomenclature History
- Previous Names
-
- unm_sa1753
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable SUMO ligase activity; transcription coregulator activity; and transcription regulator inhibitor activity. Predicted to be involved in negative regulation of receptor signaling pathway via JAK-STAT; negative regulation of transcription by RNA polymerase II; and protein sumoylation. Predicted to be located in nuclear speck. Predicted to be active in chromatin and nucleoplasm. Orthologous to human PIAS1 (protein inhibitor of activated STAT 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PINIT domain | PINIT domain superfamily | SAP domain | SAP domain superfamily | Zinc finger, MIZ-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A1D5NSS2 | InterPro | 651 | ||||||
| UniProtKB:A0AC58G510 | InterPro | 648 | ||||||
| UniProtKB:A0ACD6B7P1 | InterPro | 651 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pias1a-201
(1)
|
Ensembl | 1,932 nt | ||
| mRNA |
pias1a-202
(1)
|
Ensembl | 6,002 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance