Gene
nlrp1
- ID
- ZDB-GENE-120709-59
- Name
- NLR family pyrin domain containing 1
- Symbol
- nlrp1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- null
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Autoinflammation with arthritis and dyskeratosis | 617388 | ||
| Palmoplantar carcinoma, multiple self-healing | 615225 | ||
| ?Respiratory papillomatosis, juvenile recurrent, congenital | 618803 | ||
| {Vitiligo-associated multiple autoimmune disease susceptibility 1} | 606579 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR007111 | NACHT nucleoside triphosphatase |
| Domain | IPR025307 | FIIND domain |
| Domain | IPR041075 | NOD1/2, winged helix domain |
| Domain | IPR041267 | NACHT, LRR and PYD domains-containing protein, helical domain HD2 |
| Family | IPR050637 | NLRP family, innate immunity and inflammation regulators |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Domain Details Per Protein
| Protein | Length | CARD domain | Death-like domain superfamily | FIIND domain | Leucine-rich repeat domain superfamily | NACHT, LRR and PYD domains-containing protein, helical domain HD2 | NACHT nucleoside triphosphatase | NLRP family, innate immunity and inflammation regulators | NOD1/2, winged helix domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A386CAB9
|
1355 | |||||||||
|
UniProtKB:A0A8M3B7X8
|
1346 | |||||||||
|
UniProtKB:A0A8M9PXG1
|
1381 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-66k16.28-201
(1)
|
Ensembl | 3,934 nt | ||
| mRNA |
si:ch211-66k16.28-202
(1)
|
Ensembl | 231 nt |
Interactions and Pathways
No data available
Plasmids
No data available