Gene

si:dkey-59l11.10

ID
ZDB-GENE-120703-17
Name
si:dkey-59l11.10
Symbol
si:dkey-59l11.10 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With si:dkey-59l11.10 Human Ortholog
No data available
Associated With si:dkey-59l11.10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001870 B30.2/SPRY domain
Domain IPR003877 SPRY domain
Domain IPR003879 Butyrophylin-like, SPRY domain
Domain IPR006574 SPRY-associated
Domain IPR007111 NACHT nucleoside triphosphatase
1 - 5 of 13 Show all
Domain Details Per Protein
Protein Length B30.2/SPRY domain B30.2/SPRY domain superfamily Butyrophylin-like, SPRY domain Concanavalin A-like lectin/glucanase domain superfamily Leucine-rich repeat Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD1/2, winged helix domain P-loop containing nucleoside triphosphate hydrolase SPRY-associated SPRY domain
UniProtKB:A0A0R4IMZ0
InterPro
1028
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-59l11.10-201 (1)
Ensembl
Ensembl 645 nt
ZFIN BLAST
mRNA si:dkey-59l11.10-202 (1)
Ensembl
Ensembl 3,708 nt
ZFIN BLAST
mRNA si:dkey-59l11.10-203 (1)
Ensembl
Ensembl 3,087 nt
ZFIN BLAST
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-59L11ZFIN Curated Data
1 - 1 of 1
Show
Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_017355519 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR792418 (1)263674 nt
MegaBLAST
PolypeptideUniProtKB:A0A0R4IMZ0 (1)1028 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
No data available
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