Gene
mef2ab
- ID
- ZDB-GENE-120614-2
- Name
- myocyte enhancer factor 2ab
- Symbol
- mef2ab Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity and protein dimerization activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yogev et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| coronary artery disease | Alliance | {Coronary artery disease, autosomal dominant, 1} | 608320 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Holliday junction regulator protein family C-terminal | MADS MEF2-like | Transcription factor, MADS-box | Transcription factor, MADS-box superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q358
|
421 | ||||
|
UniProtKB:A0A8M9PKK7
|
303 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mef2ab-201
(1)
|
Ensembl | 1,212 nt | ||
| mRNA |
mef2ab-202
(1)
|
Ensembl | 1,186 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance