Gene
bach2a
- ID
- ZDB-GENE-120525-2
- Name
- BTB and CNC homology 1, basic leucine zipper transcription factor 2a
- Symbol
- bach2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in head and trunk. Orthologous to human BACH2 (BTB domain and CNC homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Cohen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 60 | Alliance | Immunodeficiency 60 and autoimmunity | 618394 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR004826 | Basic leucine zipper domain, Maf-type |
| Domain | IPR004827 | Basic-leucine zipper domain |
| Family | IPR050457 | Zinc finger and BTB domain-containing |
| Homologous_superfamily | IPR008917 | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR046347 | Basic-leucine zipper domain superfamily |
Domain Details Per Protein
| Protein | Length | Basic-leucine zipper domain | Basic leucine zipper domain, Maf-type | Basic-leucine zipper domain superfamily | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Transcription factor, Skn-1-like, DNA-binding domain superfamily | Zinc finger and BTB domain-containing |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:X1WCB1
|
761 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bach2a-201
(1)
|
Ensembl | 7,591 nt | ||
| mRNA |
bach2a-202
(1)
|
Ensembl | 3,268 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance