Gene
bach2a
- ID
- ZDB-GENE-120525-2
- Name
- BTB and CNC homology 1, basic leucine zipper transcription factor 2a
- Symbol
- bach2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Is expressed in head; myotome; somite; somite border; and trunk. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Cohen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 60 | Alliance | Immunodeficiency 60 and autoimmunity | 618394 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR004826 | Basic leucine zipper domain, Maf-type |
| Domain | IPR004827 | Basic-leucine zipper domain |
| Family | IPR050457 | Zinc finger and BTB domain-containing |
| Homologous_superfamily | IPR008917 | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR046347 | Basic-leucine zipper domain superfamily |
Domain Details Per Protein
| Protein | Length | Basic-leucine zipper domain | Basic leucine zipper domain, Maf-type | Basic-leucine zipper domain superfamily | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Transcription factor, Skn-1-like, DNA-binding domain superfamily | Zinc finger and BTB domain-containing |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:X1WCB1
|
761 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bach2a-201
(1)
|
Ensembl | 7,591 nt | ||
| mRNA |
bach2a-202
(1)
|
Ensembl | 3,268 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance