Gene
il21
- ID
- ZDB-GENE-120510-4
- Name
- interleukin 21
- Symbol
- il21 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable cytokine receptor binding activity. Predicted to act upstream of or within immune response. Predicted to be located in extracellular region. Is expressed in several structures, including gill; heart; immune system; liver; and muscle. Human ortholog(s) of this gene implicated in asthma; common variable immunodeficiency 11; hepatocellular carcinoma; and systemic lupus erythematosus. Orthologous to human IL21 (interleukin 21).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| common variable immunodeficiency 11 | Alliance | ?Immunodeficiency, common variable, 11 | 615767 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Four-helical cytokine-like, core | Interleukin-15/Interleukin-21 family |
|---|---|---|---|
|
UniProtKB:A1YYP5
|
151 | ||
|
UniProtKB:A0A8M2BKC7
|
144 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available