Gene

tmc5

ID

ZDB-GENE-120411-6

Name

transmembrane channel like 5

Symbol

tmc5 Nomenclature History

Previous Names

TMC5 (1)
si:dkey-202l16.5 (1)
unm_sa506 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have mechanosensitive ion channel activity. Involved in cilium movement. Localizes to cytoplasm. Orthologous to human TMC5 (transmembrane channel like 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Choksi et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmc5 Human Ortholog

No data available

Associated With tmc5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR012496	TMC domain
Family	IPR038900	Transmembrane channel-like protein

Domain Details Per Protein

Protein	Length	TMC domain	Transmembrane channel-like protein
UniProtKB:A0A8M3B8A3 InterPro	487
UniProtKB:E7FDU7 InterPro	685

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tmc5-201 (1) Ensembl	Havana	2720 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	si:dkey-202l16.5-002 (1) Ensembl	Havana	628 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations