Gene
selplg
- ID
- ZDB-GENE-120410-1
- Name
- selectin P ligand
- Symbol
- selplg Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable carbohydrate binding activity. Acts upstream of or within hematopoietic stem cell migration to bone marrow and hemopoiesis. Predicted to be located in membrane. Is expressed in cardiovascular system; head; intermediate cell mass of mesoderm; trunk; and vasculature. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human SELPLG (selectin P ligand).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Sun et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR026195 | P-selectin glycoprotein ligand 1 |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | P-selectin glycoprotein ligand 1 |
|---|---|---|---|
| UniProtKB:G4WJE8 | InterPro | 284 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
selplg-201
(1)
|
Ensembl | 1,554 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
- Baïsse, B., Spertini, C., Galisson, F., Smirnova, T., Spertini, O. (2019) The function of P-selectin glycoprotein ligand-1 is conserved from ancestral fishes to mammals. Journal of Leukocyte Biology. 106(6):1271-1283
- Esain, V., Kwan, W., Carroll, K.J., Cortes, M., Liu, S.Y., Frechette, G.M., Sheward, L.M., Nissim, S., Goessling, W., North, T.E. (2015) Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via PGE2 and P-selectin Activity. Stem cells (Dayton, Ohio). 33(8):2596-612
- Sun, G., Pan, J., Liu, K., Wang, S., Wang, X., and Wang, X. (2012) Molecular cloning and expression analysis of P-selectin glycoprotein ligand-1 from zebrafish (Danio rerio). Fish physiology and biochemistry. 38(2):555-564
- Iida, A., Sakaguchi, K., Sato, K., Sakurai, H., Nishimura, D., Iwaki, A., Takeuchi, M., Kobayashi, M., Misaki, K., Yonemura, S., Kawahara, A., and Sehara-Fujisawa, A. (2010) Metalloprotease-dependent onset of blood circulation in zebrafish. Current biology : CB. 20(12):1110-1116
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