Gene
stim2b
- ID
- ZDB-GENE-120404-3
- Name
- stromal interaction molecule 2b
- Symbol
- stim2b Nomenclature History
- Previous Names
-
- stim2
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable calcium channel regulator activity and calcium ion binding activity. Predicted to be involved in activation of store-operated calcium channel activity; cellular calcium ion homeostasis; and store-operated calcium entry. Predicted to act upstream of or within calcium ion transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Used to study brain disease. Orthologous to human STIM2 (stromal interaction molecule 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Wasilewska et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| brain disease | stim2bwaw301/waw301 (AB) | standard conditions | Wasilewska et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Stromal interaction molecule | Stromal interaction molecule, Orai1-activating region |
|---|---|---|---|---|---|
|
UniProtKB:E7FE10
|
727 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stim2b-201
(1)
|
Ensembl | 4,444 nt |
Interactions and Pathways
No data available
Plasmids
No data available