ZFIN is now using GRCz12tu for Genomic Data
Gene
stim2b
- ID
- ZDB-GENE-120404-3
- Name
- stromal interaction molecule 2b
- Symbol
- stim2b Nomenclature History
- Previous Names
-
- stim2
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium channel regulator activity. Acts upstream of or within neural retina development. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Used to study brain disease. Orthologous to human STIM2 (stromal interaction molecule 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Wasilewska et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| brain disease | stim2bwaw301/waw301 (AB) | standard conditions | Wasilewska et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | STIM1/2 | STIM1/2, EF-hand | STIM1/2, Orai1-activating region |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7FE10 | InterPro | 727 | |||||
| UniProtKB:A0AC58FZM2 | InterPro | 676 | |||||
| UniProtKB:A0AC58FZW2 | InterPro | 683 | |||||
| UniProtKB:A0AC36JWC5 | InterPro | 727 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stim2b-201
(1)
|
Ensembl | 4,444 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers