ZFIN is now using GRCz12tu for Genomic Data
Gene
grb14
- ID
- ZDB-GENE-120313-3
- Name
- growth factor receptor bound protein 14
- Symbol
- grb14 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within fin regeneration. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GRB14 (growth factor receptor bound protein 14).
- Genome Resources
-
- Alliance (1)
- Gene:100334415 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ma et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR015042 | BPS (Between PH and SH2) domain |
| Domain | IPR035034 | Grb14, SH2 domain |
| Domain | IPR039665 | APBB1IP, PH domain |
| Family | IPR039664 | GRB/APBB1IP |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | APBB1IP, PH domain | BPS (Between PH and SH2) domain | Grb14, SH2 domain | GRB/APBB1IP | PH-like domain superfamily | Pleckstrin homology domain | Ras-associating domain | SH2 domain | SH2 domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QGA2 | InterPro | 484 | ||||||||||
| UniProtKB:A0AC58GHR2 | InterPro | 524 | ||||||||||
| UniProtKB:A0AC58GHR3 | InterPro | 524 | ||||||||||
| UniProtKB:A0AC58GHR4 | InterPro | 401 | ||||||||||
| UniProtKB:A0AC58GHS6 | InterPro | 479 | ||||||||||
| UniProtKB:A0AC58GHV4 | InterPro | 524 | ||||||||||
| UniProtKB:A0AC58GHX4 | InterPro | 524 | ||||||||||
| UniProtKB:A0AC58GHZ3 | InterPro | 479 | ||||||||||
| UniProtKB:A0AC58GI01 | InterPro | 450 | ||||||||||
| UniProtKB:A0AC58GI02 | InterPro | 405 | ||||||||||
| UniProtKB:A0AC58GI24 | InterPro | 524 | ||||||||||
| UniProtKB:A0AC58GI35 | InterPro | 477 | ||||||||||
| UniProtKB:A0AC58GI41 | InterPro | 403 | ||||||||||
| UniProtKB:A0AC58GI55 | InterPro | 399 | ||||||||||
| UniProtKB:A0AC58GI57 | InterPro | 446 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance