Gene
dsg2l
- ID
- ZDB-GENE-120229-2
- Name
- desmoglein 2 like
- Symbol
- dsg2l Nomenclature History
- Previous Names
-
- Dsg beta (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10; dilated cardiomyopathy 1BB; hypotrichosis; and hypotrichosis 6. Orthologous to several human genes including DSG2 (desmoglein 2); DSG3 (desmoglein 3); and DSG4 (desmoglein 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Goonesinghe et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020894 | Cadherin conserved site |
| Domain | IPR000233 | Cadherin, Y-type LIR-motif |
| Domain | IPR002126 | Cadherin-like |
| Family | IPR009122 | Desmosomal cadherin |
| Family | IPR050971 | Cadherin domain-containing protein |
| Homologous_superfamily | IPR015919 | Cadherin-like superfamily |
| Homologous_superfamily | IPR027397 | Catenin binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cadherin conserved site | Cadherin domain-containing protein | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily | Desmosomal cadherin |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A9F2KAY0
|
1063 | |||||||
|
UniProtKB:A0A8M2BIB6
|
1063 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance