Gene

dsg2l

ID
ZDB-GENE-120229-2
Name
desmoglein 2 like
Symbol
dsg2l Nomenclature History
Previous Names
  • Dsg beta (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to desmosome. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10; dilated cardiomyopathy 1BB; hypotrichosis; and hypotrichosis 6. Orthologous to several human genes including DSG2 (desmoglein 2); DSG3 (desmoglein 3); and DSG4 (desmoglein 4).
Genome Resources
Note
No Ensembl gene model in GRCz11.
Comparative Information
Expression
All Expression Data
1 figure from Goonesinghe et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dsg2l Human Ortholog
No data available
Associated With dsg2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR000233 Cadherin, Y-type LIR-motif
Domain IPR002126 Cadherin-like
Family IPR009122 Desmosomal cadherin
Family IPR050971 Cadherin domain-containing protein
Homologous_superfamily IPR015919 Cadherin-like superfamily
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Domain Details Per Protein
Protein Length Cadherin conserved site Cadherin domain-containing protein Cadherin-like Cadherin-like superfamily Cadherin, Y-type LIR-motif Catenin binding domain superfamily Desmosomal cadherin
UniProtKB:A0A9F2KAY0 1063
UniProtKB:A0A8M2BIB6 1063
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations