Gene
map3k2
- ID
- ZDB-GENE-120215-96
- Name
- mitogen-activated protein kinase kinase kinase 2
- Symbol
- map3k2 Nomenclature History
- Previous Names
-
- si:dkey-32h20.5
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human MAP3K2 (mitogen-activated protein kinase kinase kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lu et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000270 | PB1 domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR034879 | Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain |
| Domain | IPR053793 | PB1-like domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain | PB1 domain | PB1-like domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F683 | InterPro | 623 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k2-201
(1)
|
Ensembl | 2,728 nt | ||
| mRNA |
map3k2-202
(1)
|
Ensembl | 1,848 nt |
Interactions and Pathways
No data available
Plasmids
No data available