Gene
uts2r4
- ID
- ZDB-GENE-120215-247
- Name
- urotensin-2 receptor 4
- Symbol
- uts2r4 Nomenclature History
- Previous Names
-
- si:ch73-379f7.4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable urotensin II receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; blood vessel diameter maintenance; and regulation of blood pressure. Predicted to be located in membrane. Predicted to be active in plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Quan et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Urotensin II receptor |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BJE7 | InterPro | 339 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch73-379f7.4-201
(1)
|
Ensembl | 1,020 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-379F7 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005172065 (1) | |||
| Genomic | GenBank:FP015829 (1) | 96157 nt | ||
| Polypeptide | UniProtKB:A0A8M2BJE7 (1) | 339 aa |
No data available
- Alejevski, F., Leemans, M., Gaillard, A.L., Leistenschneider, D., de Flori, C., Bougerol, M., Le Mével, S., Herrel, A., Fini, J.B., Pézeron, G., Tostivint, H. (2021) Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. Open Biology. 11:210065
- Quan, F.B., Gaillard, A.L., Alejevski, F., Pézeron, G., Tostivint, H. (2021) Urotensin II-related peptide (Urp) is expressed in motoneurons in zebrafish, but is dispensable for locomotion in larva. Peptides. 146:170675
- Zhang, X., Jia, S., Chen, Z., Chong, Y.L., Xie, H., Feng, D., Wu, X., Song, D.Z., Roy, S., Zhao, C. (2018) Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis. Nature Genetics. 50(12):1666-1673
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