Gene
gsdmea
- ID
- ZDB-GENE-120215-186
- Name
- gasdermin Ea
- Symbol
- gsdmea Nomenclature History
- Previous Names
-
- dfna5a
- si:dkey-22m8.7
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in cell death. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Is expressed in neuromast. Orthologous to human GSDME (gasdermin E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 5 | Alliance | Deafness, autosomal dominant 5 | 600994 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Gasdermin-E | Gasdermin, pore forming domain |
|---|---|---|---|
|
UniProtKB:E7F9U2
|
521 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gsdmea-201
(1)
|
Ensembl | 2,051 nt |
Interactions and Pathways
No data available
Plasmids
No data available