ZFIN ID: ZDB-GENE-120214-23
Gene Name: zinc finger protein 644b
Gene Symbol: znf644b    Nomenclature History

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Previous Name: si:ch211-15l16.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Involved in camera-type eye photoreceptor cell differentiation; neuron cellular homeostasis; and regulation of gene silencing. Predicted to localize to nucleus. Is expressed in head; midbrain; optic cup; presumptive retinal pigmented epithelium; and trunk. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ZNF644 (zinc finger protein 644).
Genome Resources: Alliance (1),  Gene:100537559 (1),  Ensembl(GRCz11):ENSDARG00000102025 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6068 Point Mutation Unknown Splice Site ENU
sa7038 Point Mutation Unknown Premature Stop ENU
sa14999 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15981 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • uot5 Small Deletion Unknown Unknown CRISPR
    uot6 Indel Unknown Unknown CRISPR
    uot7 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-znf644b 1
    MO1-znf644b N/A 1
    DISEASE ASSOCIATED WITH znf644b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    myopia Alliance Myopia 21, autosomal dominant 614167
    DISEASE ASSOCIATED WITH znf644b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process camera-type eye photoreceptor cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA znf644b-201 (1)    Ensembl 10495
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM znf644b No data available
    MARKER RELATIONSHIPS
    znf644b Contained in: [BAC] CH211-15L16 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_003198781 (1)
    Genomic RefSeq:NW_018394642 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IBX8 (1) 1267 aa
    Sequence Information (all 20)
    ORTHOLOGY for znf644b ( Chr: 6 )
    CITATIONS (14)