header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-120207-1
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: mitogen-activated protein kinase binding protein 1
Gene Symbol: mapkbp1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkey-89f23.3

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Human ortholog(s) of this gene implicated in nephronophthisis 20. Orthologous to human MAPKBP1 (mitogen-activated protein kinase binding protein 1).
GENE EXPRESSION
All Expression Data: Fig. S13 from Macia et al., 2017
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ii001 Small Deletion Exon 23 Frameshift TALEN
sa11673 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa23006 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa36331 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa42877 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa45595 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mapkbp1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    nephronophthisis 20 Nephronophthisis 20 617271
    DISEASE ASSOCIATED WITH mapkbp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process RNA splicing (more)
    Cellular Component catalytic step 2 spliceosome (more)
    Molecular Function RNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001680 (1)
  • InterPro:IPR011047 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR036322 (1)
    		•
  • PROSITE:PS50082 (1)
  • PROSITE:PS50294 (1)
    		•
  • Pfam:PF00400 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mapkbp1-201 (1) 1347
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mapkbp1 No data available
    MARKER RELATIONSHIPS
    mapkbp1Contained in: [BAC] DKEY-89F23 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009292858 (1)
    Select Tool
    Genomic GenBank:CR352284 (1) 181192bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q7W9 (1) 1614aa
    Select Tool
    Sequence Clusters UniGene:157195 (1)
    Sequence Information (all 20)
    OTHER mapkbp1 GENE PAGES
  • Alliance (1)
  • Gene:100535386 (1)
  • VEGA:OTTDARG00000038557 (1)
  • Ensembl(GRCz11):ENSDARG00000103746 (1)
    • ORTHOLOGY for mapkbp1 (Chr: 17)
    CITATIONS (16)