Gene
arhgap44b
- ID
- ZDB-GENE-120206-2
- Name
- Rho GTPase activating protein 44b
- Symbol
- arhgap44b Nomenclature History
- Previous Names
-
- arhgap44
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of Rac protein signal transduction; regulation of actin cytoskeleton organization; and regulation of dendritic spine morphogenesis. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be located in cytoplasm. Predicted to be active in several cellular components, including dendritic spine; postsynaptic density; and presynaptic active zone. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR domain | Rho GTPase-activating protein 17/44/SH3BP1-like | Rho GTPase-activating protein domain | Rho GTPase activation protein |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PXE0
|
859 | |||||
|
UniProtKB:A0A8M9Q9A4
|
856 | |||||
|
UniProtKB:A0A8M9QF17
|
729 | |||||
|
UniProtKB:A0A8M9QJD4
|
861 | |||||
|
UniProtKB:A0A8M9QN54
|
853 | |||||
|
UniProtKB:A0A8M9QN52
|
862 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgap44-201
(1)
|
Ensembl | 1,992 nt | ||
| mRNA |
arhgap44-202
(1)
|
Ensembl | 2,121 nt |
Interactions and Pathways
No data available
Plasmids
No data available