ZFIN is now using GRCz12tu for Genomic Data
Gene
pde1ca
- ID
- ZDB-GENE-111215-4
- Name
- phosphodiesterase 1C, calmodulin-dependent a
- Symbol
- pde1ca Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP/PKA signal transduction. Predicted to be active in neuronal cell body. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Orthologous to human PDE1C (phosphodiesterase 1C).
- Genome Resources
-
- Alliance (1)
- Gene:101883995 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 74 | Alliance | ?Deafness, autosomal dominant 74 | 618140 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9PY25 | InterPro | 777 |
| UniProtKB:A0AC58IS40 | InterPro | 749 |
| UniProtKB:A0AC58IS41 | InterPro | 749 |
| UniProtKB:A0AC58IS42 | InterPro | 730 |
| UniProtKB:A0AC58IS43 | InterPro | 749 |
| UniProtKB:A0AC58IS45 | InterPro | 730 |
| UniProtKB:A0AC58IS46 | InterPro | 749 |
| UniProtKB:A0AC58IS47 | InterPro | 699 |
| UniProtKB:A0AC58IS48 | InterPro | 777 |
| UniProtKB:A0AC58IS50 | InterPro | 730 |
| UniProtKB:A0AC58IS51 | InterPro | 758 |
| UniProtKB:A0AC58IS52 | InterPro | 708 |
| UniProtKB:A0AC58IS53 | InterPro | 727 |
| UniProtKB:A0AC58IS62 | InterPro | 758 |
| UniProtKB:A0AC58IS72 | InterPro | 680 |
| UniProtKB:A0AC58IS78 | InterPro | 758 |
| UniProtKB:A0AC58IS81 | InterPro | 777 |
| UniProtKB:A0AC58IS91 | InterPro | 410 |
| UniProtKB:A0AC58IS94 | InterPro | 429 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance