Gene
mast3b
- ID
- ZDB-GENE-111209-1
- Name
- microtubule associated serine/threonine kinase 3b
- Symbol
- mast3b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Orthologous to human MAST3 (microtubule associated serine/threonine kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shu et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 108 | Alliance | Developmental and epileptic encephalopathy 108 | 620115 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR015022 | Microtubule-associated serine/threonine-protein kinase, pre-PK domain |
| Domain | IPR037711 | Microtubule-associated serine/threonine-protein kinase, catalytic domain |
| Domain | IPR041489 | PDZ domain 6 |
| Family | IPR050236 | Serine/threonine-protein kinases, AGC |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR023142 | Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | Microtubule-associated serine/threonine-protein kinase, catalytic domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily | PDZ domain | PDZ domain 6 | PDZ superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinases, AGC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B3Z1
|
1441 | |||||||||||
|
UniProtKB:A0A8M3AXH0
|
1456 | |||||||||||
|
UniProtKB:A0A8M3B6T6
|
1455 | |||||||||||
|
UniProtKB:A0A8M2B2L6
|
1449 | |||||||||||
|
UniProtKB:A0A8M1RIX4
|
1434 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mast3b-201
(1)
|
Ensembl | 4,185 nt | ||
| mRNA |
mast3b-202
(1)
|
Ensembl | 7,605 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance