Gene
wnt6a
- ID
- ZDB-GENE-111114-1
- Name
- wingless-type MMTV integration site family, member 6a
- Symbol
- wnt6a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Predicted to be involved in canonical Wnt signaling pathway; cell fate commitment; and neuron differentiation. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in yolk. Orthologous to human WNT6 (Wnt family member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hino et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Wnt | Wnt-6 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1RQZ6 | InterPro | 360 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-145L22 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_002662311 (1) | 2185 nt | ||
| Genomic | GenBank:FO704744 (1) | 138319 nt | ||
| Polypeptide | UniProtKB:A0A8M1RQZ6 (1) | 360 aa |
- Gu, Q., Ali, S.F., Kanungo, J. (2020) Effects of acetyl L-carnitine on zebrafish embryos: Phenotypic and gene expression studies. Journal of applied toxicology : JAT. 41(2):256-264
- Hino, H., Nakanishi, A., Seki, R., Aoki, T., Yamaha, E., Kawahara, A., Shimizu, T., Hibi, M. (2017) Roles of maternal wnt8a transcripts in axis formation in zebrafish. Developmental Biology. 434(1):96-107
- Ramachandran, R., Zhao, X.F., and Goldman, D. (2011) Ascl1a/Dkk/ beta -catenin signaling pathway is necessary and glycogen synthase kinase-3 beta inhibition is sufficient for zebrafish retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 108(38):15858-63
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