ZFIN is now using GRCz12tu for Genomic Data
Gene

myo18b

ID
ZDB-GENE-111111-8
Name
myosin XVIIIB
Symbol
myo18b Nomenclature History
Previous Names
  • fro
  • frozen (1)
  • schläfrig (1)
  • sig (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable ATP binding activity and cytoskeletal motor activity. Acts upstream of or within sarcomerogenesis. Predicted to be part of myosin complex. Is expressed in musculature system and somite border. Used to study myopathy.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myo18b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Klippel-Feil syndrome 4 Alliance Klippel-Feil syndrome 4, autosomal recessive, with myopathy and facial dysmorphism 616549
Associated With myo18b Via Experimental Models
Human Disease Fish Conditions Citations
myopathy myo18bi311/i311 (AB) standard conditions Gurung et al., 2017
myopathy myo18bi310/i310 (AB) standard conditions Gurung et al., 2017
myopathy myo18bi230/i230 (AB) standard conditions Gurung et al., 2017
myopathy myo18bto27c/to27c (AB) standard conditions Gurung et al., 2017
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001609 Myosin head, motor domain-like
Domain IPR002928 Myosin tail
Domain IPR057772 Unconventional myosin-XVIIIa, SH3 domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Kinesin motor domain superfamily Myosin head, motor domain-like Myosin tail P-loop containing nucleoside triphosphate hydrolase Unconventional myosin-XVIIIa, SH3 domain
UniProtKB:A0A8M6Z360 InterPro 687
UniProtKB:A0AC58GNJ7 InterPro 2016
UniProtKB:A0AC58GNK2 InterPro 2100
UniProtKB:A0AC58GNK7 InterPro 2089
UniProtKB:A0AC58GNK8 InterPro 2103
UniProtKB:A0AC58GNL5 InterPro 2002
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Citations
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