Gene

stard9

ID

ZDB-GENE-111111-11

Name

StAR-related lipid transfer (START) domain containing 9

Symbol

stard9 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in vesicle transport along microtubule. Predicted to act upstream of or within microtubule-based movement. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Orthologous to human STARD9 (StAR related lipid transfer domain containing 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa5903	Allele with one point mutation	Unknown	Premature Stop	ENU
sa11459	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this)
sa12181	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa14840	Allele with one point mutation	Unknown	Premature Stop	ENU
sa15359	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16123	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16149	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16538	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa23141	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa23142	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With stard9 Human Ortholog

No data available

Associated With stard9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019821	Kinesin motor domain, conserved site
Domain	IPR001752	Kinesin motor domain
Domain	IPR002913	START domain
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily
Homologous_superfamily	IPR023393	START-like domain superfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Kinesin motor domain	Kinesin motor domain, conserved site	Kinesin motor domain superfamily	P-loop containing nucleoside triphosphate hydrolase	SMAD/FHA domain superfamily	START domain	START-like domain superfamily
UniProtKB:E7F0X8	InterPro	3594

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 17

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	stard9-201 (1) Ensembl	Ensembl		12,958 nt	Select Tool ZFIN BLAST
mRNA	stard9-202 (1) Ensembl	Ensembl		885 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-72L18	BX569781	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_001921870 (1)	12767 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX569781 (1)	170138 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:E7F0X8 (1)	3594 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance

Species	Symbol	Chromosome	Accession #	Evidence
Human	STARD9	15	Ensembl:ENSG00000159433 Gene:57519 HGNC:19162 OMIM:614642	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

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