Gene

xylt1

ID
ZDB-GENE-111017-2
Name
xylosyltransferase I
Symbol
xylt1 Nomenclature History
Previous Names
  • unm b1128 (1)
  • unm_b1128 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have protein xylosyltransferase activity. Involved in embryonic cranial skeleton morphogenesis and proteoglycan biosynthetic process. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Is expressed in cartilage element; forebrain; and opercle. Orthologous to human XYLT1 (xylosyltransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Eames et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xylt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Desbuquois dysplasia Alliance Desbuquois dysplasia 2 615777
pseudoxanthoma elasticum Alliance {Pseudoxanthoma elasticum, modifier of severity of} 264800
Associated With xylt1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR024448 Xylosyltransferase, C-terminal
Family IPR003406 Glycosyl transferase, family 14
Family IPR043538 Xylosyltransferase
Domain Details Per Protein
Protein Length Glycosyl transferase, family 14 Xylosyltransferase Xylosyltransferase, C-terminal
UniProtKB:D3J0E7 919
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations