Gene
cep152
- ID
- ZDB-GENE-111005-1
- Name
- centrosomal protein 152
- Symbol
- cep152 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have protein kinase binding activity. Predicted to be involved in centriole replication. Predicted to localize to centrosome. Human ortholog(s) of this gene implicated in Seckel syndrome 5 and primary autosomal recessive microcephaly 9. Orthologous to human CEP152 (centrosomal protein 152).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sepulveda et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 9 | Alliance | Microcephaly 9, primary, autosomal recessive | 614852 |
| Seckel syndrome 5 | Alliance | Seckel syndrome 5 | 613823 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR051235 | Centrosomal Protein 152/SHC-Transforming Protein |
Domain Details Per Protein
| Protein | Length | Centrosomal Protein 152/SHC-Transforming Protein |
|---|---|---|
|
UniProtKB:A0A8M3AZU2
|
1559 | |
|
UniProtKB:X1WBK2
|
1560 | |
|
UniProtKB:A0A8M3AWQ9
|
1550 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cep152-201
(1)
|
Ensembl | 3,730 nt | ||
| mRNA |
cep152-202
(1)
|
Ensembl | 5,185 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance