Gene
ganabb
- ID
- ZDB-GENE-110930-9
- Name
- glucosidase II alpha subunit b
- Symbol
- ganabb Nomenclature History
- Previous Names
-
- ganab
- ganaba
- ganabb
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable glucan 1,3-alpha-glucosidase activity. Predicted to be involved in N-glycan processing. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be part of glucosidase II complex. Human ortholog(s) of this gene implicated in polycystic kidney disease; polycystic kidney disease 3; and polycystic liver disease. Orthologous to human GANAB (glucosidase II alpha subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| polycystic kidney disease 3 | Alliance | Polycystic kidney disease 3 | 600666 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000322 | Glycoside hydrolase family 31, TIM barrel domain |
| Domain | IPR025887 | Glycoside hydrolase family 31, N-terminal domain |
| Domain | IPR048395 | Glycosyl hydrolase family 31, C-terminal domain |
| Homologous_superfamily | IPR011013 | Galactose mutarotase-like domain superfamily |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR017853 | Glycoside hydrolase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Galactose mutarotase-like domain superfamily | Glycoside hydrolase family 31, N-terminal domain | Glycoside hydrolase family 31, TIM barrel domain | Glycoside hydrolase superfamily | Glycosyl hydrolase, all-beta | Glycosyl hydrolase family 31, C-terminal domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q6Z9 | InterPro | 941 |
Interactions and Pathways
No data available
Plasmids
No data available