Gene
orai1a
- ID
- ZDB-GENE-110721-1
- Name
- ORAI calcium release-activated calcium modulator 1a
- Symbol
- orai1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have store-operated calcium channel activity. Predicted to be involved in store-operated calcium entry. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease and tubular aggregate myopathy. Orthologous to human ORAI1 (ORAI calcium release-activated calcium modulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 9 | Alliance | Immunodeficiency 9 | 612782 |
| tubular aggregate myopathy 2 | Alliance | Myopathy, tubular aggregate, 2 | 615883 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calcium release-activated calcium channel protein | Orai superfamily |
|---|---|---|---|
|
UniProtKB:A0A0R4IYV8
|
225 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
orai1a-201
(1)
|
Ensembl | 3,251 nt | ||
| mRNA |
orai1a-202
(1)
|
Ensembl | 1,307 nt |
Interactions and Pathways
No data available
Plasmids
No data available