Gene
cox8b
- ID
- ZDB-GENE-110620-4
- Name
- cytochrome c oxidase subunit 8B
- Symbol
- cox8b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 15. Orthologous to human COX8A (cytochrome c oxidase subunit 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Little et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase, subunit 8 | Cytochrome c oxidase, subunit 8 superfamily |
|---|---|---|---|
|
UniProtKB:X1WER9
|
73 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-88B11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001303042 (1) | 605 nt | ||
| Genomic | GenBank:BX537278 (1) | 78276 nt | ||
| Polypeptide | UniProtKB:X1WER9 (1) | 73 aa |
No data available
- Cai, W., Wang, Y., Luo, Y., Gao, L., Zhang, J., Jiang, Z., Fan, X., Li, F., Xie, Y., Wu, X., Li, Y., Yuan, W. (2023) asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function. International Journal of Molecular Sciences. 24(22):
- Li, H., Zhao, F., Cao, F., Teng, M., Yang, Y., Qiu, L. (2019) Mitochondrial dysfunction-based cardiotoxicity and neurotoxicity induced by pyraclostrobin in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 251:203-211
- Duggan, A.T., Kocha, K.M., Monk, C.T., Bremer, K., and Moyes, C.D. (2011) Coordination of cytochrome c oxidase gene expression in the remodelling of skeletal muscle. The Journal of experimental biology. 214(11):1880-1887
- Little, A.G., Kocha, K.M., Lougheed, S.C., and Moyes, C.D. (2010) Evolution of the Nuclear-Encoded Cytochrome Oxidase Subunits in Vertebrates. Physiological Genomics. 42(1):76-84
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