Gene
itgam
- ID
- ZDB-GENE-110510-4
- Name
- integrin, alpha M (complement component 3 receptor 3 subunit)
- Symbol
- itgam Nomenclature History
- Previous Names
-
- cd11b (1)
- si:dkey-32n7.5
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in cell adhesion and integrin-mediated signaling pathway. Predicted to localize to integrin complex. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M).
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002035 | von Willebrand factor, type A |
| Domain | IPR013649 | Integrin alpha-2 |
| Family | IPR000413 | Integrin alpha chain |
| Homologous_superfamily | IPR028994 | Integrin alpha, N-terminal |
| Homologous_superfamily | IPR032695 | Integrin domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
| Repeat | IPR013517 | FG-GAP repeat |
| Repeat | IPR013519 | Integrin alpha beta-propellor |
Domain Details Per Protein
| Protein | Length | FG-GAP repeat | Integrin alpha-2 | Integrin alpha beta-propellor | Integrin alpha chain | Integrin alpha, N-terminal | Integrin domain superfamily | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IME5
|
738 | ||||||||
|
UniProtKB:R4GED7
|
232 | ||||||||
|
UniProtKB:A0A0R4IJT2
|
780 |
Interactions and Pathways
No data available
Plasmids
No data available