Gene
itgam.2
- ID
- ZDB-GENE-110510-4
- Name
- integrin, alpha M (complement component 3 receptor 3 subunit), tandem duplicate 2
- Symbol
- itgam.2 Nomenclature History
- Previous Names
-
- cd11b (1)
- itgam
- si:dkey-32n7.5
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be part of integrin complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in lupus nephritis; persistent fetal circulation syndrome; and pre-eclampsia. Orthologous to several human genes including ITGAM (integrin subunit alpha M) and ITGAX (integrin subunit alpha X).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8N7UVW7 | InterPro | 1132 |
Interactions and Pathways
No data available
Plasmids
No data available