Gene

ntng2b

ID

ZDB-GENE-110502-1

Name

netrin g2b

Symbol

ntng2b Nomenclature History

Previous Names

si:ch73-127k6.1

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to be involved in animal organ morphogenesis; axonogenesis; and tissue development. Orthologous to human NTNG2 (netrin G2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa9458	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa23847	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa37213	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With ntng2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia	618718

Associated With ntng2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR002049	Laminin-type EGF domain
Family	IPR050440	Laminin/Netrin Extracellular Matrix

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M3AWK1	InterPro	1520
UniProtKB:I3IT80	InterPro	230
UniProtKB:A0A8M9PQS8	InterPro	1453
UniProtKB:A0A8M3ALV5	InterPro	1579
UniProtKB:A0A8M9PUB1	InterPro	1467
UniProtKB:A0A8M9PIL9	InterPro	1502
UniProtKB:A0A8M6YUS3	InterPro	1499

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 21

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ntng2b-201 (1) Ensembl	Ensembl		739 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH73-127K6	CU915818	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_009295099 (1)	6254 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU915818 (2)	78313 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A8M3ALV5 (1)	1579 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	NTNG2	9	Ensembl:ENSG00000196358 Gene:84628 HGNC:14288 OMIM:618689	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)
Mouse	Ntng2	2	Ensembl:ENSMUSG00000035513 Gene:171171 MGI:2159341	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

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