Gene
avpr2ab
- ID
- ZDB-GENE-110411-48
- Name
- arginine vasopressin receptor 2a, duplicate b
- Symbol
- avpr2ab Nomenclature History
- Previous Names
-
- V2A(1) (1)
- si:ch211-272p8.4
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable vasopressin receptor activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; positive regulation of vasoconstriction; and regulation of systemic arterial blood pressure by vasopressin. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in X-linked nephrogenic diabetes insipidus; nephrogenic diabetes insipidus; and nephrogenic syndrome of inappropriate antidiuresis. Orthologous to human AVPR2 (arginine vasopressin receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zanardini et al., 2024
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrogenic syndrome of inappropriate antidiuresis | Alliance | Nephrogenic syndrome of inappropriate antidiuresis | 300539 |
| X-linked nephrogenic diabetes insipidus | Alliance | Diabetes insipidus, nephrogenic, 1 | 304800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Vasopressin receptor |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1QV55 | InterPro | 542 | |||
| UniProtKB:A0AB32THR6 | InterPro | 447 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
avpr2ab-201
(1)
|
Ensembl | 1,323 nt | ||
| mRNA |
avpr2ab-202
(1)
|
Ensembl | 1,306 nt | ||
| mRNA |
avpr2ab-203
(1)
|
Ensembl | 1,014 nt | ||
| mRNA |
avpr2ab-204
(1)
|
Ensembl | 1,326 nt |
Interactions and Pathways
No data available
Plasmids
No data available