Gene

ppm1ka

ID
ZDB-GENE-110411-37
Name
protein phosphatase, Mg2+/Mn2+ dependent 1Ka
Symbol
ppm1ka Nomenclature History
Previous Names
  • si:ch211-149b19.3
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1ka Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
maple syrup urine disease Alliance Maple syrup urine disease, mild variant 615135
Associated With ppm1ka Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain IPR001932 PPM-type phosphatase-like domain
Family IPR015655 Protein phosphatase 2C
Homologous_superfamily IPR036457 PPM-type phosphatase-like domain superfamily
Domain Details Per Protein
Protein Length PPM-type phosphatase, divalent cation binding PPM-type phosphatase-like domain PPM-type phosphatase-like domain superfamily Protein phosphatase 2C
UniProtKB:E7FAZ1 358
UniProtKB:A0A8M3B6G2 370
UniProtKB:A0A8M9P5N7 290
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript si:ch211-149b19.3-203 (1) Ensembl 1,592 nt
mRNA ppm1k-203 (1) Ensembl 3,708 nt
mRNA si:ch211-149b19.3-202 (1) Ensembl 1,392 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations