Gene

ltc4s

ID
ZDB-GENE-110411-32
Name
leukotriene C4 synthase
Symbol
ltc4s Nomenclature History
Previous Names
  • si:dkey-33h4.2
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have glutathione peroxidase activity; glutathione transferase activity; and leukotriene-C4 synthase activity. Predicted to be involved in leukotriene biosynthetic process. Predicted to localize to endoplasmic reticulum and nuclear envelope. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LTC4S (leukotriene C4 synthase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ltc4s Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukotriene C4 synthase deficiency 614037
Associated With ltc4s Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
Family IPR001446 5-lipoxygenase-activating protein
Homologous_superfamily IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily
Domain Details Per Protein
Protein Length 5-lipoxygenase-activating protein Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
UniProtKB:E7F8E5 153
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations