Gene
mid1
- ID
- ZDB-GENE-110411-205
- Name
- midline 1
- Symbol
- mid1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of microtubule cytoskeleton organization. Predicted to be located in microtubule. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome. Orthologous to human MID1 (midline 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Opitz GBBB syndrome | Alliance | Opitz GBBB syndrome | 300000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003649 | B-box, C-terminal |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR017903 | COS domain |
| Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
| Domain | IPR040859 | Midline-1, COS domain |
| Domain | IPR047095 | Midline-1, B-box-type 1 zinc finger |
| Family | IPR050617 | E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | B-box, C-terminal | B-box-type zinc finger | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | COS domain | E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Midline-1, B-box-type 1 zinc finger | Midline-1, COS domain | SPRY domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AWB4
|
667 | ||||||||||||||||||
|
UniProtKB:A0A8M3B2Y2
|
453 |
Interactions and Pathways
No data available
Plasmids
No data available