Gene
aff2
- ID
- ZDB-GENE-110411-190
- Name
- AF4/FMR2 family, member 2
- Symbol
- aff2 Nomenclature History
- Previous Names
-
- si:ch211-76h4.1
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of gene expression. Predicted to localize to ELL-EAF complex. Human ortholog(s) of this gene implicated in fragile X syndrome. Is expressed in intermediate cell mass of mesoderm. Orthologous to human AFF2 (AF4/FMR2 family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Armant et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked intellectual developmental disorder 109 | Alliance | Intellectual developmental disorder, X-linked 109 | 309548 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AF4/FMR2, C-terminal homology domain | AF4/FMR2 family | AF4 interaction motif |
|---|---|---|---|---|
|
UniProtKB:E7F2E1
|
1269 |
Interactions and Pathways
No data available
Plasmids
No data available