Gene

itgam.1

ID
ZDB-GENE-110411-175
Name
integrin, alpha M (complement component 3 receptor 3 subunit), tandem duplicate 1
Symbol
itgam.1 Nomenclature History
Previous Names
  • cd11b (1)
  • si:dkey-32n7.4 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to be involved in cell adhesion and integrin-mediated signaling pathway. Predicted to localize to integrin complex. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to several human genes including ITGAX (integrin subunit alpha X).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itgam.1 Human Ortholog
No data available
Associated With itgam.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR013649 Integrin alpha, first immunoglubulin-like domain
Domain IPR048285 Integrin alpha, second immunoglobulin-like domain
Domain IPR048633 Integrin alpha-X-like, third Ig-like domain
Family IPR000413 Integrin alpha chain
Homologous_superfamily IPR028994 Integrin alpha, N-terminal
Homologous_superfamily IPR032695 Integrin domain superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Repeat IPR013517 FG-GAP repeat
Repeat IPR013519 Integrin alpha beta-propellor
Domain Details Per Protein
Protein Length FG-GAP repeat Integrin alpha beta-propellor Integrin alpha chain Integrin alpha, first immunoglubulin-like domain Integrin alpha, N-terminal Integrin alpha, second immunoglobulin-like domain Integrin alpha-X-like, third Ig-like domain Integrin domain superfamily von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:F1QSJ9 1136
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-32n7.4-201 (1) Ensembl 5,121 nt
mRNA si:dkey-32n7.4-202 (1) Ensembl 3,411 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations