ZFIN is now using GRCz12tu for Genomic Data
Gene
gbe1a
- ID
- ZDB-GENE-110411-171
- Name
- glucan (1,4-alpha-), branching enzyme 1a
- Symbol
- gbe1a Nomenclature History
- Previous Names
-
- si:ch211-213e17.1
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable 1,4-alpha-glucan branching enzyme activity; cation binding activity; and hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in glycogen biosynthetic process. Human ortholog(s) of this gene implicated in glycogen storage disease IV; nervous system disease; and pulmonary tuberculosis. Orthologous to human GBE1 (1,4-alpha-glucan branching enzyme 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycogen storage disease IV | Alliance | Glycogen storage disease IV | 232500 |
| Polyglucosan body disease, adult form | 263570 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004193 | Glycoside hydrolase, family 13, N-terminal |
| Domain | IPR006047 | Glycosyl hydrolase family 13, catalytic domain |
| Domain | IPR006048 | Alpha-amylase/branching enzyme, C-terminal all beta |
| Family | IPR037439 | 1,4-alpha-glucan-branching enzyme |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR017853 | Glycoside hydrolase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | 1,4-alpha-glucan-branching enzyme | Alpha-amylase/branching enzyme, C-terminal all beta | Glycoside hydrolase, family 13, N-terminal | Glycoside hydrolase superfamily | Glycosyl hydrolase, all-beta | Glycosyl hydrolase family 13, catalytic domain | Immunoglobulin E-set | Immunoglobulin-like fold |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1RDT8 | InterPro | 687 | ||||||||
| UniProtKB:A0A2R8QQ91 | InterPro | 687 | ||||||||
| UniProtKB:A0ACD6B7Z8 | InterPro | 687 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers