ZFIN is now using GRCz12tu for Genomic Data
Gene
si:zfos-588f8.1
- ID
- ZDB-GENE-110411-111
- Name
- si:zfos-588f8.1
- Symbol
- si:zfos-588f8.1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and actin filament binding activity. Predicted to be involved in actin filament-based movement and lamellipodium morphogenesis. Predicted to act upstream of or within Rho protein signal transduction. Predicted to be located in cytoplasm. Predicted to be part of myosin complex. Predicted to be active in actin filament; lamellipodium; and ruffle. Orthologous to human MYO9B (myosin IXB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR001609 | Myosin head, motor domain-like |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR028557 | Unconventional myosin-IXb, Rho-GAP domain |
| Domain | IPR036023 | Class IX myosin, motor domain |
| Family | IPR046987 | Unconventional class IX myosin |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C1-like domain superfamily | Class IX myosin, motor domain | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain-like | P-loop containing nucleoside triphosphate hydrolase | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Ras-associating domain | Rho GTPase-activating protein domain | Rho GTPase activation protein | Ubiquitin-like domain superfamily | Unconventional class IX myosin | Unconventional myosin-IXb, Rho-GAP domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B5A2 | InterPro | 2281 | |||||||||||||
| UniProtKB:A0AB13A9I2 | InterPro | 2241 | |||||||||||||
| UniProtKB:A0AB32T8X3 | InterPro | 2203 | |||||||||||||
| UniProtKB:A0AB32T8X9 | InterPro | 2212 | |||||||||||||
| UniProtKB:A0AB32TAK8 | InterPro | 2131 | |||||||||||||
| UniProtKB:A0AB32TBH0 | InterPro | 2116 | |||||||||||||
| UniProtKB:A0AB32TBS5 | InterPro | 2163 | |||||||||||||
| UniProtKB:A0AB32TEA3 | InterPro | 2281 | |||||||||||||
| UniProtKB:A0AB32TEG3 | InterPro | 2147 | |||||||||||||
| UniProtKB:A0AB32TFS6 | InterPro | 2243 | |||||||||||||
| UniProtKB:A0AB32TFY9 | InterPro | 2238 | |||||||||||||
| UniProtKB:A0AB32TG02 | InterPro | 2265 | |||||||||||||
| UniProtKB:A0AB32THH1 | InterPro | 2250 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:zfos-588f8.1-201
(1)
|
Ensembl | 1,194 nt | ||
| mRNA |
si:zfos-588f8.1-202
(1)
|
Ensembl | 6,674 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance