limk1b

ID

ZDB-GENE-110411-106

Name

LIM domain kinase 1b

Symbol

limk1b Nomenclature History

Previous Names

si:ch211-13l22.4

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm; neuron projection; and nucleus. Orthologous to human LIMK1 (LIM domain kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With limk1b Human Ortholog

No data available

Associated With limk1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain	IPR001478	PDZ domain
Domain	IPR001781	Zinc finger, LIM-type
Family	IPR050940	Actin-regulating Serine/Threonine Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily