ZFIN is now using GRCz12tu for Genomic Data
Gene
tgm1l2
- ID
- ZDB-GENE-110408-37
- Name
- transglutaminase 1 like 2
- Symbol
- tgm1l2 Nomenclature History
- Previous Names
-
- TG1-96 (1)
- si:ch1073-138d10.1
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in keratinocyte differentiation and peptide cross-linking. Predicted to act upstream of or within keratinization. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1. Orthologous to human TGM1 (transglutaminase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001102 | Transglutaminase, N-terminal |
| Domain | IPR002931 | Transglutaminase-like |
| Domain | IPR008958 | Transglutaminase, C-terminal |
| Family | IPR050779 | Protein-glutamine gamma-glutamyltransferases |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR036238 | Transglutaminase, C-terminal domain superfamily |
| Homologous_superfamily | IPR036985 | Transglutaminase-like superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin E-set | Immunoglobulin-like fold | Papain-like cysteine peptidase superfamily | Protein-glutamine gamma-glutamyltransferases | Transglutaminase, C-terminal | Transglutaminase, C-terminal domain superfamily | Transglutaminase-like | Transglutaminase-like superfamily | Transglutaminase, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AVQ9 | InterPro | 853 | |||||||||
| UniProtKB:A0AC58IMJ0 | InterPro | 853 | |||||||||
| UniProtKB:A0AC58IMK9 | InterPro | 853 | |||||||||
| UniProtKB:A0AC58IMP4 | InterPro | 853 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tgm1l2-201
(1)
|
Ensembl | 7,446 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers