Gene
ggt1b
- ID
- ZDB-GENE-110408-13
- Name
- gamma-glutamyltransferase 1b
- Symbol
- ggt1b Nomenclature History
- Previous Names
-
- si:dkey-47k14.1
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have glutathione hydrolase activity and peptidyltransferase activity. Predicted to be involved in several processes, including peptide metabolic process; response to estradiol; and response to lipopolysaccharide. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sant et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| gamma-glutamyl transpeptidase deficiency | Alliance | ?Glutathioninuria | 231950 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000101 | Gamma-glutamyltranspeptidase |
| Homologous_superfamily | IPR029055 | Nucleophile aminohydrolases, N-terminal |
| Homologous_superfamily | IPR043137 | Gamma-glutamyltranspeptidase, small subunit |
| Homologous_superfamily | IPR043138 | Gamma-glutamyltranspeptidase, large subunit, C-terminal domain |
Domain Details Per Protein
| Protein | Length | Gamma-glutamyltranspeptidase | Gamma-glutamyltranspeptidase, large subunit, C-terminal domain | Gamma-glutamyltranspeptidase, small subunit | Nucleophile aminohydrolases, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:F8W5P0
|
574 |
Interactions and Pathways
No data available
Plasmids
No data available