slc25a38b

ID

ZDB-GENE-110214-1

Name

solute carrier family 25 member 38b

Symbol

slc25a38b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable glycine transmembrane transporter activity. Involved in erythrocyte differentiation. Acts upstream of or within hemoglobin biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in blood; blood island; and posterior cardinal vein. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 2. Orthologous to human SLC25A38 (solute carrier family 25 member 38).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Fernández-Murray et al., 2016

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc25a38b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive pyridoxine-refractory sideroblastic anemia 2	Alliance	Anemia, sideroblastic, 2, pyridoxine-refractory	205950

Associated With slc25a38b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR002067	Mitochondrial carrier protein
Family	IPR030847	Mitochondrial glycine transporter Hem25/SLC25A38
Homologous_superfamily	IPR023395	Mitochondrial carrier domain superfamily
Repeat	IPR018108	Mitochondrial substrate/solute carrier