Gene

fam120a

ID

ZDB-GENE-110131-10

Name

family with sequence similarity 120 member A

Symbol

fam120a Nomenclature History

Previous Names

im:7152789

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Orthologous to human FAM120A (family with sequence similarity 120 member A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7152789 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa2594	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa35099	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa35100	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With fam120a Human Ortholog

No data available

Associated With fam120a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

No data available

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 11

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fam120a-201 (1) Ensembl	Ensembl	5,244 nt	Select Tool ZFIN BLAST
mRNA	fam120a-203 (1) Ensembl	Ensembl	3,042 nt	Select Tool ZFIN BLAST
ncRNA	fam120a-002 (1) Ensembl	Ensembl	744 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-14F19	BX601648	ZFIN Curated Data
Encodes	EST	IMAGE:7152789	CK689620	Thisse et al., 2004

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Sequences

Type	Accession #	Sequence	Length (nt/aa)	Analysis
RNA	RefSeq:NR_023337 (1)		631 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX601648 (1)		230457 nt	Select Tool MegaBLAST

Orthology

Comparative Orthology: Alliance

Species	Symbol	Chromosome	Accession #	Evidence
Human	FAM120A	9	Ensembl:ENSG00000048828 Gene:23196 HGNC:13247 OMIM:612265	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)
Mouse	Fam120a	13	Ensembl:ENSMUSG00000038014 Gene:218236 MGI:2446163	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

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