Gene

mical2a

ID
ZDB-GENE-110110-2
Name
microtubule associated monooxygenase, calponin and LIM domain containing 2a
Symbol
mical2a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have several functions, including FAD binding activity; NADPH:sulfur oxidoreductase activity; and actin binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to localize to filamentous actin and microtubule organizing center. Is expressed in fin; heart; heart tube; and pharyngeal arch. Orthologous to human MICAL2 (microtubule associated monooxygenase, calponin and LIM domain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Xue et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mical2a Human Ortholog
No data available
Associated With mical2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001715 Calponin homology domain
Domain IPR001781 Zinc finger, LIM-type
Domain IPR002938 FAD-binding domain
Family IPR029939 MICAL2
Homologous_superfamily IPR036188 FAD/NAD(P)-binding domain superfamily
Homologous_superfamily IPR036872 CH domain superfamily
Domain Details Per Protein
Protein Length Calponin homology domain CH domain superfamily FAD-binding domain FAD/NAD(P)-binding domain superfamily MICAL2 Zinc finger, LIM-type
UniProtKB:E5F2M4 268
UniProtKB:X1WDB4 834
UniProtKB:A0A2R8QRE8 538
UniProtKB:F1QKD2 711
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations