Gene
rspo4
- ID
- ZDB-GENE-110103-2
- Name
- R-spondin 4
- Symbol
- rspo4 Nomenclature History
- Previous Names
-
- si:dkey-107i16.4
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 4. Orthologous to human RSPO4 (R-spondin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nonsyndromic congenital nail disorder 4 | Alliance | Anonychia congenita | 206800 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR043601 | R-spondin, Fu-CRD domain |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
| Repeat | IPR006212 | Furin-like repeat |
Domain Details Per Protein
| Protein | Length | Furin-like repeat | Growth factor receptor cysteine-rich domain superfamily | R-spondin, Fu-CRD domain | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:M5AN99
|
241 |
Interactions and Pathways
No data available
Plasmids
No data available