Gene

bicc1a

ID

ZDB-GENE-101223-3

Name

BicC family RNA binding protein 1a

Symbol

bicc1a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Is expressed in midbrain hindbrain boundary and pronephric duct. Orthologous to human BICC1 (BicC family RNA binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bicc1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
diffuse cystic renal dysplasia	Alliance	{Renal dysplasia, cystic, susceptibility to}	601331

Associated With bicc1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR004087	K Homology domain
Domain	IPR004088	K Homology domain, type 1
Domain	IPR037974	BICC1, SAM domain
Domain	IPR047549	BICC1, first type I KH domain
Domain	IPR047553	BICC1, third type I KH domain
Domain	IPR047554	BICC1, second type I KH
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR036612	K Homology domain, type 1 superfamily

Domain Details Per Protein

Protein	Length	BICC1, first type I KH domain	BICC1, SAM domain	BICC1, second type I KH	BICC1, third type I KH domain	K Homology domain	K Homology domain, type 1	K Homology domain, type 1 superfamily	Sterile alpha motif domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M3AIX6 InterPro	954
UniProtKB:A0A8M9PP15 InterPro	990
UniProtKB:X1WGP5 InterPro	955

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	bicc1a-201 (1) Ensembl	Ensembl		5,627 nt	Select Tool
mRNA	bicc1a-202 (1) Ensembl	Ensembl		1,946 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations