Gene

mmel1

ID
ZDB-GENE-101112-2
Name
membrane metallo-endopeptidase-like 1
Symbol
mmel1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human MMEL1 (membrane metalloendopeptidase like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa9984Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa11076Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa41905Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With mmel1 Human Ortholog
No data available
Associated With mmel1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008753 Peptidase M13, N-terminal domain
Domain IPR018497 Peptidase M13, C-terminal domain
Family IPR000718 Peptidase M13
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR042089 Peptidase M13, domain 2
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Domain Details Per Protein
Protein Additional Resources Length Metallopeptidase, catalytic domain superfamily Peptidase M13 Peptidase M13, C-terminal domain Peptidase M13, domain 2 Peptidase M13, N-terminal domain
UniProtKB:A0A140LH71 InterPro 765
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mmel1-202 (1)
Ensembl
Ensembl 3,375 nt
ZFIN BLAST
mRNA mmel1-203 (1)
Ensembl
Ensembl 2,476 nt
ZFIN BLAST
mRNA mmel1-204 (1)
Ensembl
Ensembl 2,446 nt
ZFIN BLAST
ncRNA mmel1-002 (1)
Ensembl
Ensembl 517 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-222L21ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_017358367 (1)4288 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:AL954137 (1)222162 nt
MegaBLAST
PolypeptideUniProtKB:A0A140LH71 (1)765 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanMMEL11
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseMmel14
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
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