Gene
plch2b
- ID
- ZDB-GENE-101112-1
- Name
- phospholipase C, eta 2b
- Symbol
- plch2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity and phosphatidylinositol phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid metabolic process. Orthologous to human PLCH2 (phospholipase C eta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR015359 | Phosphoinositide-specific phospholipase C, EF-hand-like domain |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | PH-like domain superfamily | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C family | Phosphoinositide-specific phospholipase C, EF-hand-like domain | Phospholipase C, phosphatidylinositol-specific, Y domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PVI9 | InterPro | 1260 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plch2b-201
(1)
|
Ensembl | 4,553 nt | ||
| mRNA |
plch2b-202
(1)
|
Ensembl | 2,340 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance