ZFIN is now using GRCz12tu for Genomic Data
Gene
fmn2a
- ID
- ZDB-GENE-101107-1
- Name
- formin 2a
- Symbol
- fmn2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in formin-nucleated actin cable assembly. Predicted to act upstream of or within actin nucleation. Predicted to be located in actin filament and cytoplasm. Predicted to be active in endoplasmic reticulum membrane; microtubule cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 47. Orthologous to human FMN2 (formin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 47 | Alliance | Intellectual developmental disorder, autosomal recessive 47 | 616193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin Homology | Formin homology family, Cappuccino subfamily |
|---|---|---|---|---|---|---|
| UniProtKB:F1Q9W7 | InterPro | 595 | ||||
| UniProtKB:X1WC43 | InterPro | 1465 | ||||
| UniProtKB:A0A8M9P0I6 | InterPro | 1445 | ||||
| UniProtKB:A0A8M9PV94 | InterPro | 334 | ||||
| UniProtKB:A0ACD6B718 | InterPro | 1465 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers