Gene
lonrf4
- ID
- ZDB-GENE-101021-4
- Name
- LON peptidase N-terminal domain and ring finger 4
- Symbol
- lonrf4 Nomenclature History
- Previous Names
-
- lonrf1
- si:ch1073-193f3.1
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
la018991Tg | Transgenic insertion | Unknown | Unknown | DNA | |
sa9353 | Allele with one point mutation | Unknown | Unknown | ENU | |
sa19088 | Allele with one point mutation | Unknown | Unknown | ENU | |
sa35722 | Allele with one point mutation | Unknown | Missense, Splice Site | ENU |
1 - 4 of 4
Show
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
Domain | IPR001841 | Zinc finger, RING-type |
Domain | IPR003111 | Lon protease, N-terminal domain |
Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
1 - 5 of 9 Show all
Domain Details Per Protein
Protein | Length | Lon protease, N-terminal domain | Lon protease, N-terminal domain superfamily | PUA-like superfamily | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QPJ1
|
596 | |||||||||
UniProtKB:A0A8M9PSI9
|
596 | |||||||||
UniProtKB:A0A8M9PFK7
|
608 | |||||||||
UniProtKB:A0A8M9QGU3
|
608 |
1 - 4 of 4
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
lonrf1-201
(1)
|
Ensembl | 5,581 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-22O18 | ||
Contained in | BAC | CH73-337P4 | ||
Contained in | BAC | DKEY-14M2 | ||
Contained in | Fosmid | CH1073-193F3 | ZFIN Curated Data |
1 - 4 of 4
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_021474313 (1) | 4331 nt | ||
Genomic | GenBank:BX088721 (1) | 231054 nt | ||
Polypeptide | UniProtKB:A0A8M9PFK7 (1) | 608 aa |
No data available
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Weger, B.D., Sahinbas, M., Otto, G.W., Mracek, P., Armant, O., Dolle, D., Lahiri, K., Vallone, D., Ettwiller, L., Geisler, R., Foulkes, N.S., and Dickmeis, T. (2011) The light responsive transcriptome of the zebrafish: function and regulation. PLoS One. 6(2):e17080
- Gavriouchkina, D., Fischer, S., Ivacevic, T., Stolte, J., Benes, V., and Dekens, M.P. (2010) Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells. PLoS One. 5(9):e12542
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
1 - 5 of 5
Show